Roxithromycin side chain

Roxithromycin is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the lactone ring This result suggests that HMR 3004 (the strongest inhibitory drug, likely owing to its quinoline side chain) and roxithromycin act on a cellular target upstream of

AIM To investigate the metabolism of roxithromycin. tRXMi in rat liver thylation and oxime ether side chain O-dealkylation are main biotransi39orrnation

Sep 12, 2006 Roxithromycin is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the method for the determination of roxithromycin in bulk and pharmaceutical However, an N-oxime side chain is attached to the lactone ring. It is also currently Roxithromycin is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the lactone ring

Roxithromycin drug information DrugsUpdate India

Roxithromycin is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the Identification of the metabolites of roxithromycin in humans. Zhong D 4) hydrolysis of the cladinose moiety and 5) dealkylation of the oxime ether side chain

Methods: The degradation kinetics and products of roxithromycin were investigated in simulated Although the presence of the oxime ether side chain at the 9- May 1, 2000 The semisynthetic antibiotic roxithromycin (RXM) exists in an of the cladinose moiety and 5) dealkylation of the oxime ether side chain